微流體生物芯片
Cellix公司推出的整套VenaFluxTM 微流體細胞分析平臺是該公司目前最受客戶歡迎的一套系統,提供在活細胞水平上微流體活性篩選的完整解決方案。操作簡單,分析效率高,可大大提高藥品的開發和篩選效率。
VenaFlux 系統是第一個能進行連續流體細胞分析的半自動化微流體分析系統。配合使用Cellix生物芯片和細胞分析軟件,VenaFlux 系統可檢測粘附到微毛細管上的細胞,微毛細管中覆蓋抗體或者培養有內皮細胞,模擬生理流動產生一定的剪切力。VenaFlux系統操作簡單,可減少耗時耗錢的動物模型實驗,獲得特異性強,準確性高,重復性好的結果。
Cellix提供一系列的生物芯片包括Vena8內皮細胞+TM,Vena8熒光+ TM,Vena8TM(定制Vena8系列);Vena Delta系列;Vena4YTM;Vena4Y2TM和VenaECTMbiochips。
所有生物芯片模擬人體的毛細血管,通過串聯的模式連接各部件,在Cellix工作站使用。
微流體生物芯片的主要特點:
Vena4Y2TM Biochip:For dual injection assays and Thrombosis studies mimicking branching micro blood vessels
The Vena4Y2™ Biochip is Cellix’s first biochip containing a branching microchannel and is compatible with fluorescent microscopy. Using Cellix’s MirusTM Nanopump, cells and drug compounds may be perfused via dual-injection at the Y-channel end facilitating laminar flow of two streams.
This biochip is ideal for studying chemotactic gradients via dual-injection and thrombosis at the site of such branching micro blood vessels as seen in vivo.
Vena4Y2TM Biochips are supplied in packs of 10, facilitating 40 experiments per pack.
Features· 20x, 40x, 60x long working distance magnification microscopy.
Brightfield / Phase contrast / Fluorescent microscopy.
Suitable for a wide range of cell suspensions and whole blood.
Easy to coat microcapillaries with a range of different adhesion molecules.
Biochip plastic is optically clear permitting detailed microscopy studies.
0.05 – 450 dyne/cm2 shear stresses / shear flow rates easily obtained and controlled by the MirusTM Nanopump and FlowAssayTM software.
Shear stress / Shear flow rate may be preset to be incrementally increased during an assay.
Real time imaging under flow conditions.
Vena4Y2TM Biochip: For dual injection assays and Thrombosis studies mimicking branching micro blood vessels.